Research Highlights
Innovative Sequencing Technologies
We invent novel methods to map RNA modifications like m6A and pseudouridine at single-base resolution, pushing the boundaries of what's possible in epitranscriptomics.
Cell Lineage Tracing
Using DNA mutations as a "molecular clock", we reconstruct developmental histories to understand how complex organisms are built from a single cell.
Latest News
- Dec 2025 The Chang Ye Lab officially opens at The Hong Kong Polytechnic University. Welcome!